US Scientists Awarded 2024 Nobel Prize for Breakthrough in Gene Regulation
Victor Ambros and Gary Ruvkun, two scientists from the United States, were awarded the 2024 Nobel Prize in Medicine for their groundbreaking discovery of microRNA and its crucial role in gene regulation.
Announced by the Nobel Assembly at Sweden’s Karolinska Institute, their work solved a long-standing mystery in biology. As the jury emphasized that improper gene regulation can lead to serious diseases, including cancer, diabetes, and autoimmune disorders, highlighting the significance of their findings for multicellular organisms, including humans.
Ruvkun expressed his surprise at receiving the prestigious award, noting the considerable media attention that followed and described the experience as a significant shift from previous accolades.
He and Ambros, who have been friends for many years, celebrated the news with a congratulatory video call, showcasing their close collaboration throughout their research.
The pair’s research focused on the roundworm C. elegans, where they identified microRNA as a new class of small RNA molecules that are vital for gene regulation. This discovery allows cells to selectively utilize relevant genetic instructions. Their pivotal findings were published in two articles in 1993 and have since paved the way for further understanding of various biological processes and diseases.
As the Nobel Prize includes a diploma, a gold medal, and a $1 million award to be shared between the two, it marks a significant recognition of their contributions to science. The Nobel season continues with announcements for the physics and chemistry prizes, followed by literature and peace prizes later in the week.
